The Gut Bacteria's connection with depression, diabetes, and cancer. - Seeker's Thoughts

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The Gut Bacteria's connection with depression, diabetes, and cancer.

Thoughts and emotions are connected by the brain, and due to a few pieces of research, it very odd to find the connection between your gut bacteria and mood, behavior and disease. 

The facts are unexpected and shocking as gut bacteria live in colonies in our intestines. There are 300 to 500 different kinds of bacteria containing nearly 2 million genes in your guts.
The bacteria live throughout your body, but the ones in your gut may have the biggest impact on your well-being. 

They line your entire digestive system. Most live in your intestines and colon. They affect everything from your metabolism to your mood to your immune system.
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The gut is a second brain- Yes!

There are millions of microbes in the gut, and logically gut reacts as a second brain. Do you remember when you are scared, you might pee yourself?

However, the priority given was to the brain, which is not always true. Signals can come through guts as well.

How does the gut connect with depression?

The Neurotransmitter serotonin is connected with anxiety and depression. The gut has more concentration of serotonin receptors than the brain does. 

Gut Bacteria and Social Behaviour

The gut bacteria impact so much on social behavior that adding good bacteria in guts can help humans.
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They can be used as anti-depressant instead of medicines. The whole perspective of emotions change since some connection between gut bacteria and human emotion is found.  So, the overall connection of body- the production of hormones and fitness impacts upon the emotional state of the brain not only the external factors. 

How does gut bacteria link with diseases?

Research found that Gut bacteria may guard against diabetes that comes with aging.
According to researchers report in Science Translational Medicine. Old mice have less Akkermansia muciniphila bacteria the young mice do, that loss triggers inflammation, which eventually leads cells to ignore signals from the hormone insulin.

Such disregard for insulin’s message to take in glucose is known as insulin resistance and is a hallmark of type 2 diabetes.

Your gut bacteria affect your body’s metabolism. They determine things like how many calories you get from food and what kinds of nutrients you draw from it. Too much gut bacteria can make you turn fiber into fatty acids.

This may cause fat deposits in your liver, which can lead to something called “metabolic syndrome” -- a condition that often leads to type 2 diabetes, heart disease, and obesity.

 Studies show that people with colon cancer have a different gut microbiota, including higher levels of disease-causing bacteria than healthy people.

What is the gut?

The gastrointestinal tract (digestive tract, digestion tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients and expels the remaining waste as feces. 

What are Akkermansia muciniphila bacteria?

Akkermansia muciniphila is a species of human intestinal mucin-degrading bacterium, the type species for a new genus, Akkermansia, proposed in 2004 by Muriel Derrien and others. Extensive research is being undertaken to understand the association with obesity, diabetes, and inflammation.

What exactly the researchers have found?

Researchers have suspected that bacteria and other microbes in the gut are involved in aging, but how the microbes influence the process hasn’t been clear.  

The mice lose A.muciniphila, also called Akk and friendly microbes that help break down dietary fiber into short-chain fatty acids, such as butyrate and acetate. Those fatty acids signal bacteria and human cells to perform certain functions.

Treating old mice and elderly rhesus macaques with an antibiotic called enrofloxacin increased the abundance of AKK in the animal’s guts and made cells respond to insulin again. 

Giving old animal’s butyrate had the same effect, suggesting that there may be multiple ways to head off insulin resistance in other people in the future.

Moods can come from within and emotions are part of the human mind. However, the bacteria which live in guts impact the brain though it does not impact upon the visuals.

Yet it can send a signal to the brain related to morality and fear, emotions and social behavior.  

It also makes sense people who have Irritable bowel syndromes- tend to get more depressed.  If people worry too much, they should see their diet and health of their gut bacteria. More research is needed in this field.

Understanding bacteria- All bacteria are not bad.

Cleaning all bacteria is not a good thing. Some bacteria help cleaning, put on weight and being courageous and happier. Having good bacteria and some bad will create a balance as killing all bacteria creates more allergies among humans.

How to increase gut bacteria?

 Regretfully there has to be changed in the diet to increase gut bacteria. Start by eating a nutritious diet high in fiber-rich foods, like fruits, vegetables, and whole grains. A “western” diet that’s high in fat and sugar and low in fiber can kill certain types of gut bacteria, making your microbiota less diverse.

Exercise can also encourage the growth of a variety of gut bacteria. Having a more varied gut microbiota may promote better health and, in turn, reduce your risk of disease.



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